UNIVERSITÀ DEGLI STUDI DI SIENA
UNIVERSITÀ DEGLI STUDI DI SIENA
What can we learn from Africa?
New insights to lymphoma classification, heterogeneity, molecular epidemiology
& biology
Certosa di Pontignano Siena, 7-8 may 2010
Thursday 6 may
18.00
registration
19.30-22.00
Welcome Cocktail
Friday 7 may
9.00-10.00
Registration and Coffee
10.00-10.15
Introduction
I. Magrath, INCTR, Bruxelles, Belgium
10.15-10.30
NCI’s perspectives and funding and training opportunities
Mostafa Nokta, NCI - Bethesda , USA
10.30-10.45
Feasibility of using the WHO lymphoma classification in the context of diagnostic practice in Africa - a pathologist's perspective'
Shaheen Sayed, Aga Khan University Hospital Nairobi, Kenya
10.45-13.00 BURKITT LYMPHOMA
Chairman: Lorenzo Leoncini
The Burkitt Tumor. Lessons and reminiscences (15 min)
Lucio Luzzatto, ITT, Italy
Revisiting the diagnosis of Burkitt lymphoma in light of recent developments (15 min)
Lorenzo Leoncini, University of Siena, Italy
PRESENTATION OF SELECTED CASES
1280/09– Burkitt’s Lymphoma vs Lymphoblastic Lymphoma (10 min)
Dr I Bovani APOF - Lacor Hospital, Uganda
How to make a diagnosis of BL with a limited panel of antibodies?
Naresh Kikkeri, Imperial College London, UK (30 min including discussion)
13.00 Lunch
14.00-16.00 HODGKIN LYMPHOMA
Chairman: Kikkeri Naresh
Hodgkin lymphoma – New concepts in the WHO classification 2008 (30 min)
Stefano Pileri, University of Bologna, Italy
PRESENTATION OF SELECTED CASES
Are there special aspects or attributes to classical Hodgkin lymphoma seen in the developing world? (30 min including discussion)
Naresh Kikkeri, Imperial College London, UK
16.00 Coffee Break
16.30-18.30 DLBCL
Chairman: Martine Raphael
Morphological, immunophenotypic and genetic heterogeneity of DLBCL (30 min)
H. Stein, Charitè University Berlin, Germany
PRESENTATION OF SELECTED CASES
423/08 B Cell Lymphoma, unclassifiable, with features intermediate between Burkitt’s Lymphoma and Diffuse Large B- Cell Lymphoma (10 min)
Dr K Schurfeld APOF Lacor Hospital, Uganda
Intermediate cases between BL and DLBCL is likely to be a real disease entity: a lesson from African cases (30 min including discussion)
Martine Raphael, University Paris Sud, France
20.30 Social Dinner
Saturday 8 may
9.00-10.30: SMALL B CELL LYMPHOMA
Chairman: Nina Hurwitz
Small B-cell lymphomas. New Concepts in the WHO classification 2008 (30 min)
M. Piris, CNIO, Madrid, Spain
PRESENTATION OF SELECTED CASES
Small B-cell lymphomas in Africa - is it under-diagnosed? (30 min including discussion)
Nina Hurwitz, Basel, Switzerland
10.30 Coffee break
11.00-13.00: HIV and HHV8 RELATED LYMPHOMA
Chairman: Leona Ayers
HIV associated lymphomas (15 min)
Martine Raphael, University Paris Sud, France
HHV-8 associated lymphoprolipherative disorders: primary effusion lymphoma (PEL) and Castleman disease (15 min)
Ethel Ceserman, Cornell University, NewYork
PRESENTATION OF SELECTED CASES
Atypical lymphoproliferative disorders in HIV positive patients in the developing world (30 min including discussion)
Leona Ayers, Ohio University
13.00 Lunch
14.00-14.30
Malignancies mimicking lymphomas – how to differentiate these from lymphomas on morphology with or without a limited panel of immunostains?
Anita Borges, Bombay, India
14.30-15.00
Therapeutic implications of incorrect diagnosis of malignancies mimicking lymphomas.
Emanuele Zucca, Bellinzona, Switzerland
15.00-15.30 SPECIAL SEMINAR INVITED BY THE ISTITUTO TOSCANO TUMORI (ITT)
Is intensive chemotherapy for aggressive and highly aggressive non Hodgkin’s lymphomas necessary in Africa, and is it feasible?
Nicholas Abinya, Kenya
15.30-16.00
How to treat and manage HIV-associated lymphomas in the developing world?
Mark Bower, Imperial College London, UK
16.00-16.30 Coffee Break
16.30-18.00
Round Table
Chairman: Kikkeri Naresh
Practical recommendations for improving lymphoma diagnosis in Africa
How can WHO classification be adapted for the practice of lymphoma pathology in developing countries?
Ethical issues associated with designing treatment protocols specifically for developing countries.
Is there a need alternate treatment protocols for adult lymphomas in Africa with treatment regimens different from those used in the Western countries?
Role of telemedicine in improving diagnostics and management of lymphomas in Africa.
The biological basis of epidemiological differences in lymphomas across the world - a route for future research
18.00 Conclusion Kikkeri Naresh, I. Magrath, Lorenzo Leoncini
20.00 Dinner