University of Siena

VI EWDD

Sixth European Workshop in Drug Design

June 03 - 09, 2007 - Certosa di Pontignano, Siena (Italy)

PROGRAMME

PRESENTATIONS and PICTURES

The University of Siena is pleased to announce the sixth edition of its unique Workshop for researchers at Universities and in the Pharmaceutical Industry, to be held in Certosa di Pontignano, Siena, Italy, on June, 3^th – 10^th 2007.

The Sixth European Workshop in Drug Design will allow 65 participating scientists to work closely with 20 leading researchers from both drug industry and academic institutions in exploring solutions to concrete problems encountered in the drug design and discovery process. Like in the previous editions (for example IV EWDD and V EWDD), the goal of the Workshop is to help participants to collect, interpret and use experimental data to design new drugs using new methods of molecular modelling in conjunction with synthetic feasibility concepts and metabolic pathways. Interaction of these studies with strategies adopted in the Pharmaceutical Industries, such as high-throughput screening, will be explored.

Each workshop topic will be considered in terms of individual tasks and their inter-relationships within the discovery cycle. The major topics will be the following: ligand/structure based drug design, in silico ADME - Tox and metabolism, design and screening of virtual libraries, molecular modelling methodologies, cheminformatics/bioinformatics and synthetic feasibility. These topics will be covered by lectures in the mornings.

The goal of the afternoon working sessions is to create, using case studies, an environment that is similar to what happens inside pharmaceutical companies today. The participants will be divided into teams which will be led and coordinated by tutors who are research group leaders in their companies and Universities. Each teams will work through a different drug design case, emulating a real research team. The team's work will be focused on rational design and will include writing reports, project status reviews, and planning events of real-life research teams, as well as in-depth work with appropriate modelling software.

With the purpose to stimulate helpful discussions, attendees will be invited to present in poster format their own research problems. Participation in the Sixth European Workshop in Drug Design is limited to 65 applicants, selected on the basis of individual experience.

To apply, please submit your name, address, affiliation, and primary area of research, along with a curriculum vitae, by fax or mail/E-mail to:

Fee for participation (Euro 2,500.00 ) will include all meals and participation in social events and hotel accommodation in two-bed rooms for seven nights (some single rooms are also available, supplementary fee Euro 300.00).

Some financial aid will be available for applicants.

Bentham Science Publishers Ltd will offer:

• a free personal subscription to Bentham to the attendee presenting the most interesting poster. 
• 20% subscription discounts to Bentham to all attendees.

Deadline for applications is March 31st, 2007

WORKSHOP FACULTY (preliminary) Wolfram Altenhofen Chemical Computing Group Inc., Germany Hugues-Olivier Bertrand Accelrys, France Andrea Cavalli University of Bologna, Italy Gabriele Cruciani University of Perugia, Italy Gerhard F. Ecker University of Wien, Austria Gerd Folkers Collegium Helveticum University and ETH Zürich, Switzerland Jas Gata-Aura Schrödinger GmbH – Germany Hans-Dieter Höltje University of Düsseldorf – Germany  Ismail Ijjaali Aureus Pharma William L. Jorgensen Yale University, USA Hugo Kubinyi Germany Thierry Langer University of Innsbruck, Austria Garland Marshall Washington University, USA Eric Martin Novartis Corp. – Emeryville, USA Adriano Martinelli University of Pisa, Italy Jonathan Mason Lundbeck Research DK -Copenhagen, Denmark Stefano Moro University of Padova, Italy Ferran Sanz Biomedical Research Park - Barcelona, España Brian Schoichet UCSF – San Francisco, USA Hanoch Senderowitz Epix Pharmaceuticals Ltd., Israel Wolfgang Sippl University of Halle, Germany James P. Snyder Emory University, USA Anna Tramontano University 'La Sapienza'-Roma, Italy Veljko Veljkovic Institute of Nuclear Sciences VINCA-Belgrade, Yugoslavia Rebecca Wade Germany Andrea Zaliani Lilly Forschung gmbH, Germany

SCIENTIFIC COMMITTEE Prof. Maurizio Botta University of Siena, Italy Prof. Gabriele Cruciani University of Perugia, Italy Prof. Hugo Kubinyi Germany Prof. Thierry Langer University of Innsbruck, Austria Dr. Alessandro Padova Siena Biotech s.p.a., Italy Prof. Anna Tramontano University ‘La Sapienza’ - Roma, Italy

LOCAL ORGANIZING COMMITTEE Prof. Maurizio Botta University of Siena, Italy Prof. Federico Corelli University of Siena, Italy Dr. Fabrizio Manetti University of Siena, Italy Prof. Andrea Tafi University of Siena, Italy

Organizing Secretariat: